I am down to get some frog gut shots
This is my argument for government science budgets.
Headline: Scientists Spend Millions Studying Andean Frog Fucking Habits!
“What a waste!”
What if I told you those scientists were making more frogs to study how they can freeze solid and thaw out? Or how limb regeneration works?
Practically all meds come from science like that.
why are you studying Easter island soil? discovery of Rapamicin and the cell cenesense pathways in human cells.
They needn’t worry unless the mouse experimental animal Union is more powerful than theirs.
Salient points for those who don’t want to read the article, or can’t:
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The team administered a single shot of E. americana intravenously to mice with colorectal cancer, and it completely eliminated tumors in every treated animal.
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Caused only short-lived inflammatory effects that resolved within 72 hours
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Over two months of observation, treated mice showed no signs of organ damage or chronic toxicity.
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The bacterium are also sensitive to antibiotics, providing intervention options if problems were to arise following treatment.
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When the mice were later re-exposed to cancer cells, none developed new tumors, suggesting the treatment had triggered long-lasting immune memory.
This holds some real promise, I’m very excited to see what this brings! Kudos to the researchers!
Mfw bacteria become resistant: 😱😱😱
Le epic bacteriophage
Still probably better than cancer, no ?
Yes, now you have to shove a live frog up your ass every day or die of colon cancer.
Multiresistant bacteria are a death sentence in many cases…
and cancer isn’t?
In many cases it isn’t.
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Getting news from memes is next level.
Awesome!
… we’ll never hear about this again.
Just a minute at 2000°C also eliminated all cancer cells in mice.
But no immune memory.
oh, the immune system will remember, all your cells will remember
Did we read the same paper? Not a single case of regression after treatment.
They were talking about the downsides of treatment via 2000 °C.
Yeah so was I. But they’re wrong, like I said no specimen had cancer return after the 2000⁰C treatment.
True, but by a different mechanism. Immune memory was not involved in their continued resistance.
Yes, this.
Impact on the remaining cells still requires further studying
That is outside of the scope of this study however.
It turns out that the witch who turned the prince into a frog was actually curing his cancer not cursing him.
Ah yes, Thermotherapy
I bet I can do the same in under 10 s.
If this takes off it could be a great thing for conservation. Frogs are in a lot of trouble!
Sadly I’m not so sure, but I like to be optimistic
If this
takes offLeaps off
Do I eat frog poop or should I suckle on their anus for best results?
“when administered intravenously”, so you inject their poop
Neither. Vore time
Gale: Stop licking the damn thing!
How do you administer handgun for colon cancer? 😳
You shouldn’t. The side effects turn out to usually be more harmful than the cancer.
Skill issue
afraid to ask: did it also eliminate the mice?
What’s more, the response wasn’t just rapid but appeared to provide ongoing protection. When the mice were later re-exposed to cancer cells, none developed new tumors
Apparently it made them stronger
Please stop praying for my mice, they’ve become too strong. One of them chewed through the fridge
Quite the contrary…
first, it has a natural affinity for the low-oxygen environment inside solid tumors, so within just 24 hours it had increased its numbers by around 3,000-fold, but it also didn’t drift over to impact any other healthy organs or tissue. Then it’s able to directly kill the growth thanks to toxins it secretes inside the tumor.
At the same time, the bacterial invasion triggered a natural immune response, and the tumors soon became flooded with immune cells – particularly neutrophils, and T and B cells – alongside increases in inflammatory signaling molecules. The combined effect was widespread tumor cell death driven both by direct bacterial action from the foreign gut bug and by the host’s own immune system.
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Importantly, this mechanism appears to also be highly tumor-specific, with E. americana sticking only to the tumor environment. The researchers believe this selectivity arises from a combination of factors unique to tumors – insufficient oxygen (hypoxia), leaky blood vessels, altered metabolism and locally suppressed immune defenses that allow the bacterial colony to thrive where they are also most destructive.
Shit thats a lot of promising routes of action and modulation.
:bufo-offers-gut-bacterium:
